Determination of isoniazid in human urine using screen-printed carbon electrode modified with poly-L-histidine

MF Bergamini, DP Santos, MVB Zanoni - Bioelectrochemistry, 2010 - Elsevier
A sensitive voltammetric method for trace measurements of isoniazid (INZ) in synthetic
human urine sample is described. The method is based on its electroreduction at− 0.98 V vs.
Ag/AgCl on screen-printed carbon electrode (SPCE) modified with poly-l-histidine (PH). A
film of good adherence on SPCE and electrocatalytic properties was obtained coating the
electrode by histidine monomer electropolymerization process (SPCE/EPH). The
electrochemical behavior of the modified SPCE was investigated by cyclic, linear sweep …
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