Development and validation of a machine learning individualized treatment rule in first-episode schizophrenia
Importance Little guidance exists to date on how to select antipsychotic medications for
patients with first-episode schizophrenia. Objective To develop a preliminary individualized
treatment rule (ITR) for patients with first-episode schizophrenia. Design, Setting, and
Participants This prognostic study obtained data from Taiwan's National Health Insurance
Research Database on patients with prescribed antipsychotic medications, ambulatory
claims, or discharge diagnoses of a schizophrenic disorder between January 1, 2005, and …
patients with first-episode schizophrenia. Objective To develop a preliminary individualized
treatment rule (ITR) for patients with first-episode schizophrenia. Design, Setting, and
Participants This prognostic study obtained data from Taiwan's National Health Insurance
Research Database on patients with prescribed antipsychotic medications, ambulatory
claims, or discharge diagnoses of a schizophrenic disorder between January 1, 2005, and …
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