2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

…, Z Demetrashvili, I Di Carlo, S Di Saverio… - World Journal of …, 2019 - Springer
In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and
severity in many countries worldwide. The increase in CDI incidence has been particularly …

Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis

…, A Bellacosa, A Protti, A Di Sapio… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people …

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

…, F Goupil, C Leroyer, D Gourcerol, T Didi… - The Lancet …, 2019 - thelancet.com
Background Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal
antibody that has been shown to safely reduce exacerbations and improve lung function for …

Direct-acting antivirals after successful treatment of early hepatocellular carcinoma improve survival in HCV-cirrhotic patients

…, A Licata, I Scalisi, G Mazzola, MA Di Rosolini… - Journal of …, 2019 - Elsevier
Background & Aims The effectiveness of direct-acting antivirals (DAAs) against hepatitis C
virus (HCV), following successful treatment of early hepatocellular carcinoma (HCC), has …

2019 WSES guidelines for the management of severe acute pancreatitis

…, L Ansaloni, W Biffl, F Coccolini, S Di Saverio… - World journal of …, 2019 - Springer
Although most patients with acute pancreatitis have the mild form of the disease, about 20–30%
develops a severe form, often associated with single or multiple organ dysfunction …

Avelumab plus axitinib versus sunitinib for advanced renal-cell carcinoma

…, S Hariharan, B Huang, A Di Pietro… - … England Journal of …, 2019 - Mass Medical Soc
Background In a single-group, phase 1b trial, avelumab plus axitinib resulted in objective
responses in patients with advanced renal-cell carcinoma. This phase 3 trial involving …

Wireless communications through reconfigurable intelligent surfaces

E Basar, M Di Renzo, J De Rosny, M Debbah… - IEEE …, 2019 - ieeexplore.ieee.org
… This article has been presented in part at the 2019 European Conference on Networks and
… As of mid-2019, 5G wireless networks have been already deployed in certain countries, …

GENCODE reference annotation for the human and mouse genomes

…, J Chrast, F Cunningham, T Di Domenico… - Nucleic acids …, 2019 - academic.oup.com
The accurate identification and description of the genes in the human and mouse genomes
is a fundamental requirement for high quality analysis of data informing both genome biology …

Adaptive mutability of colorectal cancers in response to targeted therapies

…, M Gherardi, MC Lagomarsino, F Di Nicolantonio… - Science, 2019 - science.org
The emergence of drug resistance limits the efficacy of targeted therapies in human tumors.
The prevalent view is that resistance is a fait accompli: when treatment is initiated, cancers …

The concise guide to pharmacology 2019/20: Ion channels

…, P Davies, M Delling, F Di Virgilio… - British journal of …, 2019 - Wiley Online Library
… The landscape format of the Concise Guide is designed to facilitate comparison of related
targets from material contemporary to mid-2019, and supersedes data presented in the 2017/…