PURPOSE: The incidental discovery of adrenal masses has become a common clinical
problem. We address current trends in clinical, endocrine, radiological and scintigraphic
evaluation, and strategies for management of adrenal masses. A diagnostic and therapeutic
algorithm is suggested. MATERIALS AND METHODS: A comprehensive review of the
literature was performed using MEDLINE, bibliographies of select articles, current issues of
peer reviewed general medicine, endocrinology, diagnostic imaging and surgical journals …

The growing demand for imaging tests and the progressive aging of the population have led
to a progressive increase in the detection of indeterminate adrenal lesions. Once an adrenal
incidentaloma is detected, clinical and hormone tests together with a battery of imaging
techniques (CT, MRI, PET/CT…) make it possible to determine the cause in most cases. In
this article, we discuss the advantages and limitations of each technique. We show the
imaging characteristics of the most common adrenal lesions and propose a diagnostic …