Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids
Background The microbiome has been implicated in the initiation and persistence of
inflammatory bowel disease. Despite the fact that diet is one of the most potent modulators of
microbiome composition and function and that dietary intervention is the first-line therapy for
treating pediatric Crohn's disease, the relationships between diet-induced remission,
enteropathy, and microbiome are poorly understood. Here, we leverage a naturally-
occurring canine model of chronic inflammatory enteropathy that exhibits robust remission …
inflammatory bowel disease. Despite the fact that diet is one of the most potent modulators of
microbiome composition and function and that dietary intervention is the first-line therapy for
treating pediatric Crohn's disease, the relationships between diet-induced remission,
enteropathy, and microbiome are poorly understood. Here, we leverage a naturally-
occurring canine model of chronic inflammatory enteropathy that exhibits robust remission …
[引用][C] Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids. Microbiome. 2019 …
S Wang, R Martins, MC Sullivan, ES Friedman… - … doi. org/10.1186/s40168-019-0740 …
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