Differences in airway structural changes assessed by 3-dimensional computed tomography in asthma and asthma–chronic obstructive pulmonary disease overlap

M Niwa, T Fujisawa, M Karayama, K Furuhashi… - Annals of Allergy …, 2018 - Elsevier
Background Asthma–chronic obstructive pulmonary disease (COPD) overlap (ACO) is a
clinical phenotype sharing features of asthma and COPD. Multidetector row computed
tomography (MDCT) can be used to evaluate the airway structure; however, differences
between asthma and ACO seen on MDCT are poorly understood. Objective To investigate
the difference in airway structural between asthma and ACO, using MDCT in patients with
clinical asthma. Methods Sixty-four patients with asthma were allocated to an asthma group …
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