Differential responses of the insular cortex gyri to autonomic challenges

PM Macey, P Wu, R Kumar, JA Ogren… - Autonomic …, 2012 - Elsevier
Determining insular functional topography is essential for assessing autonomic
consequences of neural injury. We examined that topography in the five major insular cortex
gyri to three autonomic challenges, the Valsalva, hand grip, and foot cold pressor, using
functional magnetic resonance imaging (fMRI) procedures. Fifty-seven healthy subjects
(age±std: 47±9years) performed four 18s Valsalva maneuvers (30mm Hg load pressure),
four hand grip challenges (16s at 80% effort), and a foot cold pressor (60s, 4° C), with fMRI …
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