Dissecting the role of redox signaling in neuronal development

DA Bórquez, PJ Urrutia, C Wilson… - Journal of …, 2016 - Wiley Online Library
The generation of abnormally high levels of reactive oxygen species (ROS) is linked to
cellular dysfunction, including neuronal toxicity and neurodegeneration. However,
physiological ROS production modulates redox‐sensitive roles of several molecules such as
transcription factors, signaling proteins, and cytoskeletal components. Changes in the
functions of redox‐sensitive proteins may be important for defining key aspects of stem cell
proliferation and differentiation, neuronal maturation, and neuronal plasticity. In neurons …

Dissecting the role of redox signaling in neuronal development

D Bórquez Muñoz, PJ Urrutia, C Wilson, B Van Zundert… - 2016 - repositorio.uchile.cl
The generation of abnormally high levels of reactive oxygen species (ROS) is linked to
cellular dysfunction, including neuronal toxicity and neurodegeneration. However,
physiological ROS production modulates redox-sensitive roles of several molecules such as
transcription factors, signaling proteins, and cytoskeletal components. Changes in the
functions of redox-sensitive proteins may be important for defining key aspects of stem cell
proliferation and differentiation, neuronal maturation, and neuronal plasticity. In neurons …
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