Objective Data Preconception or early administration of low-dose aspirin might improve
endometrial growth, placental vascularization, and organogenesis. Most studies have
evaluated the potential benefit of preconception or early administration of low-dose aspirin
in women with a history of recurrent pregnancy loss, women who have undergone in vitro
fertilization, or women with thrombophilia or antiphospholipid syndrome. These women are
at an increased risk of placenta-associated complications of pregnancy, including …