Dose‐escalated radiotherapy for clinically localized and locally advanced prostate cancer

YH Lee, JY Lee, TW Kang, TH Kong… - Cochrane Database …, 2023 - cochranelibrary.com
YH Lee, JY Lee, TW Kang, TH Kong, MH Kim, SH You
Cochrane Database of Systematic Reviews, 2023cochranelibrary.com
Background Treatments for clinically localized prostate cancer include radical
prostatectomy, external beam radiation therapy, brachytherapy, active surveillance,
hormonal therapy, and watchful waiting. For external beam radiation therapy, oncological
outcomes may be expected to improve as the dose of radiotherapy (RT) increases.
However, radiation‐mediated side effects on surrounding critical organs may also increase.
Objectives To assess the effects of dose‐escalated RT in comparison with conventional …
Background
Treatments for clinically localized prostate cancer include radical prostatectomy, external beam radiation therapy, brachytherapy, active surveillance, hormonal therapy, and watchful waiting. For external beam radiation therapy, oncological outcomes may be expected to improve as the dose of radiotherapy (RT) increases. However, radiation‐mediated side effects on surrounding critical organs may also increase.
Objectives
To assess the effects of dose‐escalated RT in comparison with conventional dose RT for curative treatment of clinically localized and locally advanced prostate cancer.
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