Dose finding in a low-dose 21-day combined oral contraceptive containing gestodene
F Lüdicke, H Sullivan, J Spona, M Elstein - Contraception, 2001 - Elsevier
An open label, non-comparative study was carried out in 22 women over a total of five
cycles. After an untreated cycle, oral administration of 20 μg ethinyl estradiol (EE) with 50 μg
gestodene (GST)(tablets taken daily for 21 days with a break of 7 days) was commenced,
and three treatment cycles were followed by an untreated follow-up control cycle. The ability
of this formulation to inhibit ovulation and suppress ovarian activity was assessed by using
hormonal parameters and ultrasound. One ovulation occurred during treatment. Luteinized …
cycles. After an untreated cycle, oral administration of 20 μg ethinyl estradiol (EE) with 50 μg
gestodene (GST)(tablets taken daily for 21 days with a break of 7 days) was commenced,
and three treatment cycles were followed by an untreated follow-up control cycle. The ability
of this formulation to inhibit ovulation and suppress ovarian activity was assessed by using
hormonal parameters and ultrasound. One ovulation occurred during treatment. Luteinized …
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