… of murine monoclonal antibody to human tumour necrosis … that used murine monoclonal
antibodies to human TNFα (… in a randomised, placebo-controlled, double-blind, clinical trial …

… Treatment of acute peritonitis in young swine with gentamicin and a monoclonal antibody
against tumor necrosis factor. Presented at the 31st Interscience Conference on Antimicrobial …

… We have reported a successful randomised, controlled trial of a specific cytokine-blocking
agent in rheumatoid arthritis. Preliminary data from the use of … This clinical trial was funded by …

… A humanised monoclonal antibody to human TNF-α, CDP571, was constructed by linking …
TNF monoclonal antibody to a human IgG4 antibody. Three phase II trials suggested that …

… human TNFα expressing transgenic mice in a dose dependent manner and is currently
being evaluated in clinical trials … After completing the double blind portion of the trial, patients …

… CNS radiation necrosis, we conducted a placebo-controlled double-blind study to determine
the extent … , administered every 3 weeks, could reduce active radiation necrosis in the CNS. …

… The results of this double blind, placebo controlled trial revealed … with chimeric monoclonal
antibodies to tumor necrosis factor … therapy with monoclonal antibody to tumor necrosis factor …

… ) is the first fully human anti-TNFα monoclonal antibody to enter clinical trials for the treatment
of … , defined as all randomised patients who received at least one double blind injection of …

… activity score (DAS)22 >3.2, who were enrolled in a double blind, multicentre clinical trial
with anti-TNFα monoclonal antibody (D2E7) at our centre, were studied. Disease modifying …

… that block the effects of tumour necrosis factor (TNF) α, … the studies referenced have only
been published in abstract form. In a randomised, double blind, placebo controlled phase I study…