Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib
A Idbaih, K Mokhtari, JF Emile, D Galanaud, H Belaid… - Neurology, 2014 - AAN Enterprises
A Idbaih, K Mokhtari, JF Emile, D Galanaud, H Belaid, S de Bernard, N Benameur…
Neurology, 2014•AAN EnterprisesHistiocytic sarcoma (HS) is classified within the malignant histiocytic disorders. 1
Involvement of isolated CNS in HS, termed primary CNS-HS (PCNS-HS), is characterized by
a proliferation of cells in the monocyte/macrophage lineage within the CNS. 2–6 This case
report documents the clinical, biological, pathologic, and radiologic spectrums of PCNS-HS.
Involvement of isolated CNS in HS, termed primary CNS-HS (PCNS-HS), is characterized by
a proliferation of cells in the monocyte/macrophage lineage within the CNS. 2–6 This case
report documents the clinical, biological, pathologic, and radiologic spectrums of PCNS-HS.
Histiocytic sarcoma (HS) is classified within the malignant histiocytic disorders.1 Involvement of isolated CNS in HS, termed primary CNS-HS (PCNS-HS), is characterized by a proliferation of cells in the monocyte/macrophage lineage within the CNS.2–6 This case report documents the clinical, biological, pathologic, and radiologic spectrums of PCNS-HS.
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