Drivers of the decision to biopsy and follow-up of small suspicious thyroid nodules
ABSTRACT Objective: In 2015, the updated American Thyroid Association (ATA) guidelines
recommended observation for suspicious subcentimeter thyroid nodules, based on their
indolent course. We aimed to evaluate the frequency of biopsy in suspicious thyroid nodules
since the introduction of these guidelines, including factors contributing to clinical decision-
making in a tertiary care center. Methods: We conducted a retrospective study of patients in
the Mayo Clinic, Rochester, Minnesota, with new, subcentimeter suspicious thyroid nodules …
recommended observation for suspicious subcentimeter thyroid nodules, based on their
indolent course. We aimed to evaluate the frequency of biopsy in suspicious thyroid nodules
since the introduction of these guidelines, including factors contributing to clinical decision-
making in a tertiary care center. Methods: We conducted a retrospective study of patients in
the Mayo Clinic, Rochester, Minnesota, with new, subcentimeter suspicious thyroid nodules …
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