In a constantly changing environment, neuronal circuits need to be updated and adjusted to
elicit directed actions. Synaptic plasticity plays an important role in modulating such globally
and locally acting networks. The active zone (AZ) is a protein-rich compartment of chemical
synapses, where precisely orchestrated molecular interactions control synaptic vesicle (SV)
fusion with the presynaptic membrane. The subsequent release of neurotransmitter
substances onto postsynaptic receptor fields forms the basis of neuronal communication …