Systemic infections, especially in patients with chronic diseases, may result in sepsis: an
explosive, uncoordinated immune response that can lead to multisystem organ failure with a
high mortality rate. Patients with similar clinical phenotypes or sepsis biomarker expression
upon diagnosis may have different outcomes, suggesting that the dynamics of sepsis is
critical in disease progression. A within-subject study of patients with Gram-negative
bacterial sepsis with surviving and fatal outcomes was designed and single-cell …

Systemic infections, especially in patients with chronic diseases, may result in sepsis: an
explosive immune response that can lead to multisystem organ failure with a high mortality
rate. Patients with similar clinical phenotypes or sepsis biomarker expression upon
diagnosis may have different outcomes, suggesting that the dynamics of sepsis is critical in
disease progression. A within-subject study of patients with Gram-negative bacterial sepsis
with surviving and fatal outcomes was designed and single-cell transcriptomic analyses of …