… -mediated adverse reactions including hepatic damage. These treatments are … Clinical
Practice Guidelines (CPGs) is to provide guidance to hepatologists, internists and other clinical …

EASL Clinical Practice Guidelines (CPG) on the management of cholestatic … The EASL CPG
on the management of cholestatic liver diseases aim to provide current recommendations on …

… Our understanding of genetic risk factors for DILI is still in its infancy; describing the known
genetic associations with diverse drugs is beyond the scope of this clinical practice guideline ( …

… disease. AIH can be associated with a number of other hepatic conditions, in particular the
cholestatic liver diseases… (PSC), but also with drug-induced liver injury (DILI), alcoholic or non-…

… guidance on DILI, the recent European Association for the Study of the Liver (EASL) clinical
practice guidelines … close observation for potential DILI during clinical trials [47]. The survey …

… of liver injuries are based in part on criteria for drug-induced liver injury (DILI) Figure 1. …
acute liver failure in patients with drug-induced liver injury. Gastroenterology. 2014;147:109-118. …

… Idiosyncratic drug-induced liver injury mimics acute and chronic liver … Furthermore, we will
provide clinical practice-based recommendations for the diagnosis and treatment of DILI due …

… liver tests to fulminant hepatic failure. Despite recent research efforts specific biomarkers are
not still available for routine use in clinical practice… other causes of liver disease. Diagnostic …

… injuries associated with … the criteria for drug-induced liver injury – a grading of their severity,
and the diagnostic and preventive criteria for chemically induced occupational liver disease. …

… The quality of the evidence in these clinical practical guidelines (CPGs) has been classified
into one of three levels: high (A), moderate (B) or low (C). The GRADE system offers two …