Results We analyzed 531 diabetic patients, 264 (49.7%) of which received invasive strategy.
Patients managed conservatively were a subgroup characterized by older age and
cardiovascular comorbidity, increased risk of bleeding and the absence of high-risk
electrocardiogram (ECG). In diabetic patients with NSTE-ACS, independent predictors
associated with conservative strategy were low-risk ECG, initial Killip class> 1, high risk of
bleeding and pretreatment with clopidogrel. Conclusions The fear of bleeding complications …

Diabetic patients with non-ST-segment elevation acute coronary syndromes are at high risk
for subsequent cardiovascular events. At the same time, however, they derive greater benefit
than non-diabetic counterparts from an aggressive acute-phase management based on
platelet glycoprotein IIb/IIIa receptor antagonists and an early invasive strategy. Despite the
benefit, these treatment modalities remain underutilized among patients with diabetes
mellitus. The widespread use of drug-eluting stents will further improve outcomes in patients …