Abstract Background and Aims: Current diagnostic algorithms for detecting non-alcoholic
fatty liver disease (NAFLD) are based in secondary care and associated with considerable
costs and late diagnosis. We have created an integrated community based pathway utilising
transient elastography and a community hepatologist review, to stratify patients at risk of
developing NAFLD. This study investigated the cost-effectiveness from an NHS England
perspective of this innovative diagnostic pathway (IDP). Methods: Markov modelling of the …

Objectives To assess the long-term cost-effectiveness of a risk stratification pathway,
compared with standard care, for detecting non-alcoholic fatty liver disease (NAFLD) in
primary care. Setting Primary care general practices in England. Participants Adults who
have been identified in primary care to have a risk factor for developing NAFLD, that is, type
2 diabetes without a history of excessive alcohol use. Intervention A community-based
pathway, which uses transient elastography and hepatologists to stratify patients at risk of …