Importance Obesity is the leading cause of obstructive sleep apnea (OSA); however, the
effects of weight loss and lifestyle interventions on OSA and comorbidities remain uncertain.
Objective To evaluate the effect of an interdisciplinary weight loss and lifestyle intervention
on OSA and comorbidities among adults with moderate to severe OSA and overweight or
obesity. Design, Setting, and Participants The Interdisciplinary Weight Loss and Lifestyle
Intervention for OSA (INTERAPNEA) study was a parallel-group open-label randomized …