The effect of outlet obstruction on neural pathways to the bladder was examined six weeks
after urethral ligation in rats. Ligated rats exhibited a seven-fold increase in bladder weight,
a six-fold increase in volume, and significant increases (p< 0.001) in micturition pressure,
residual volume and compliance measured under urethane anesthesia. Unanesthetized
ligated rats in comparison to control rats voided smaller volumes of urine more frequently
(0.7 vs 1.1 voids/hr., p< 0.001). Electrophysiological examination of vesical afferent and …

Effect of bladder outlet obstruction on micturition reflex pathways in the rat | CiNii Research …
Effect of bladder outlet obstruction on micturition reflex pathways in the rat …