Backgrounds Global warming has increased concern about the synergistic or interactive
effects of temperature and air pollution on human health. The aim of this study was to
examine the effect of changes in season and temperature on mortality associated with air
pollution in Seoul, Korea, from June 1999 to December 2007. Methods We used Poisson
regression models with natural cubic splines. The effect of modifications was explored with
two models: a time-varying coefficient model and a temperature-stratified model. Results In …

Backgrounds: Global warming has increased concern about the synergistic or interactive
effects of temperature and air pollution on human health. The aim of this study was to
examine the effect of changes in season and temperature on mortality associated with air
pollution in Seoul, Korea, from June 1999 to December 2007. Methods: We used Poisson
regression models with natural cubic splines. The effect of modifications was explored with
two models: a time-varying coefficient model and a temperature-stratified model. Results: In …