Effect of chronic angiotensin converting enzyme inhibition on sympathetic nerve traffic and baroreflex control of the circulation in essential hypertension
G Grassi, C Turri, R Dell'Oro, ML Stella… - Journal of …, 1998 - journals.lww.com
Journal of hypertension, 1998•journals.lww.com
Background Human studies have shown that the blood pressure lowering effects of
angiotensin converting enzyme inhibitors are accompanied by a reduction in plasma
norepinephrine levels. Whether this is due to central or peripheral mechanisms is unknown,
however. Objective To evaluate the effects of chronic interference with the renin–angiotensin
system on sympathetic nerve traffic and baroreflex control of vagal and adrenergic
cardiovascular drive.
angiotensin converting enzyme inhibitors are accompanied by a reduction in plasma
norepinephrine levels. Whether this is due to central or peripheral mechanisms is unknown,
however. Objective To evaluate the effects of chronic interference with the renin–angiotensin
system on sympathetic nerve traffic and baroreflex control of vagal and adrenergic
cardiovascular drive.
Abstract
Background
Human studies have shown that the blood pressure lowering effects of angiotensin converting enzyme inhibitors are accompanied by a reduction in plasma norepinephrine levels. Whether this is due to central or peripheral mechanisms is unknown, however.
Objective
To evaluate the effects of chronic interference with the renin–angiotensin system on sympathetic nerve traffic and baroreflex control of vagal and adrenergic cardiovascular drive.
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