Effect of in ovo folic acid injection on hepatic IGF2 expression and embryo growth of broilers

Y Liu, L Zhi, J Shen, S Li, J Yao, X Yang - Journal of animal science and …, 2016 - Springer
Background Insulin-like factor 2 (IGF2) plays an important role in embryonic growth process
by modulating intermediary metabolism and cell proliferation. Folic acid is involved in one
carbon metabolism and contributes to DNA methylation which is related to gene expression.
The purpose of this study was to explore whether folic acid could regulate IGF2 expression
via epigenetic mechanism and further promote embryonic growth of new-hatched broilers.
Methods In the present study, 360 fertile eggs were selected and randomly assigned to four …

Effect of in ovo folic acid injection on hepatic IGF2 expression and embryo growth of broilers.

LYL Liu YanLi, ZLH Zhi LiHui, SJ Shen Jing… - 2016 - cabidigitallibrary.org
Abstract Background: Insulin-like factor 2 (IGF2) plays an important role in embryonic growth
process by modulating intermediary metabolism and cell proliferation. Folic acid is involved
in one carbon metabolism and contributes to DNA methylation which is related to gene
expression. The purpose of this study was to explore whether folic acid could regulate IGF2
expression via epigenetic mechanism and further promote embryonic growth of new-
hatched broilers. Methods: In the present study, 360 fertile eggs were selected and randomly …
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