Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial

PA Poole-Wilson, J Lubsen, BA Kirwan, FJ van Dalen… - The Lancet, 2004 - thelancet.com
… but their effect on clinical outcome is controversial. We aimed to investigate the effect of the
calcium antagonist nifedipine on long-term outcome in patients with stable angina pectoris. …

Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension: the ACTION trial

, … Trial Investigating Outcome with Nifedipine … - Journal of …, 2005 - journals.lww.com
… Our results in hypertensive ACTION patients assigned nifedipine show how difficult it is to
achieve control. One reason for this must be the large within-subject variability of blood …

Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS …

MJ Brown, CR Palmer, A Castaigne, PW de Leeuw… - The Lancet, 2000 - thelancet.com
… the effects of the calcium-channel blocker nifedipine once … on cardiovascular mortality and
morbidity in high risk patients … A prestudy analysis of cardiovascular morbidity in each of the …

Long-acting nifedipine in the management of the hypertensive patient

ME Snider, DS Nuzum, A Veverka - Vascular health and risk …, 2008 - Taylor & Francis
… A number of clinical trials evaluating long-acting nifedipine … the effects of nifedipine on
NE, delivery of nifedipine via … the effects of nifedipine on proteinuria and BP in patients with …

Benefits and safety of long-acting calcium antagonists in coronary artery disease: the ACTION Trial

RH Fagard - Journal of hypertension, 2005 - journals.lww.com
… The ACTION trial was a multicentre, double-blind, randomized, … the effect of long-acting
nifedipine GITS (Gastrointestinal Therapeutic System) on mortality and cardiovascular morbidity

Nifedipine and mortality: grave defects in the dossier

LH Opie, FH Messerli - Circulation, 1995 - Am Heart Assoc
… proposed adverse effects of short-acting nifedipine on mortality, even if … action, such as
verapamil, diltiazem, and amlodipine, or to any of the truly long-acting preparations of nifedipine

Long-term mortality follow-up of hospital survivors of a myocardial infarction randomized to nifedipine in the SPRINT study

H Reicher-Reiss, S Behar, V Boyko… - Cardiovascular drugs …, 1998 - Springer
… support an association between nifedipine therapy and a late harmful effect on long-term …
few years and was replaced by the long-acting slow-release compounds. These compounds …

Nifedipine: dose-related increase in mortality in patients with coronary heart disease

CD Furberg, BM Psaty, JV Meyer - Circulation, 1995 - Am Heart Assoc
… Background The purpose of this study was to assess the effect of the dose of nifedipine, a …
Compared with the long-acting formulations of nifedipine that have more recently become …

Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients

RA Kloner, GW Vetrovec, BJ Materson - The American journal of …, 1998 - Elsevier
patient-years in the comparative trials (Table III). The cardiovascular death rate among all
nifedipine GITS patients … the effects of the long-acting CCBs amlodipine and nifedipine GITS …

Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis

S Bangalore, S Parkar, FH Messerli - The American journal of medicine, 2009 - Elsevier
… evaluate the effectiveness of long-acting CCBs in patients with known coronary artery disease.
Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with …