Effect of rosmarinic acid on inhibition of gentamicin induced nephrotoxicity in rats
M Tavafi, H Ahmadvand - Tissue and Cell, 2011 - Elsevier
The present investigation reports the effect of rosmarinic acid (RA), an antioxidant on
gentamicin sulphate (GS)-induced renal oxidative damage in rats. Rosmarinic acid (RA) has
been demonstrated to have antioxidant, free radical scavenger and anti-inflamatory effects.
Twenty-eight Sprague-Dawley rats were divided in to four equal groups as follows: group 1
(control), group 2 (GS 100mg/kg/d ip), group 3 (GS 100mg/kg/d ip+ RA 50mg/kg/d) and
group 4 (GS 100mg/kg/d ip+ RA 100mg/kg/d). Treatments were administrated once daily for …
gentamicin sulphate (GS)-induced renal oxidative damage in rats. Rosmarinic acid (RA) has
been demonstrated to have antioxidant, free radical scavenger and anti-inflamatory effects.
Twenty-eight Sprague-Dawley rats were divided in to four equal groups as follows: group 1
(control), group 2 (GS 100mg/kg/d ip), group 3 (GS 100mg/kg/d ip+ RA 50mg/kg/d) and
group 4 (GS 100mg/kg/d ip+ RA 100mg/kg/d). Treatments were administrated once daily for …
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