This study is based on the need analysis that finds the phenomenon that conventional learning model has not been effective enough in developing students learning potential optimally. This study aims to know the effectiveness and difference learning result of using Collaborative-Problem Based Learning (CPBL) model on computer network subjects compared with conventional learning method. The subject of this research is the 4th semester students of Information Technology Study Program of Universitas Dharmas Indonesia as much as 42 students. Students are divided into groups of controls and experimental groups. This research uses Quasi-Experiment approach, with non-equivalent control group design. The results showed that learning model collaborative-problem based learning in computer network course is effective in imparting learnings skill and more motivated in learning, more confident and able to solve problems given, responsible and able to work together in teams, there is difference learning result of learning model of Collaborative-Problem Based Learning with conventional learning methods on cognitive and psychomotor aspects.