Effects of Sophora flavescens on the cardiac contractile and secretory functions and its alterations in the hyperthyroidism

JF Wen, SN Jin, GH Zhou… - International …, 2009 - internationaljournalofcardiology.com
Objective The roots of Sophora flavescens (SF), is a traditional Chinese medicine that has
been known to possess antiinflammatory, antiarrhythmic, vasodilatory and antihypertensive
effects. However, the effect of SF on the cardiac hormone secretion in both physiological and
pathophysiological conditions has not yet been defined. Design and methods
Hyperthyroidism was induced by administering sodium l-thyroxine (T4, 0.5 mg/kg, sc) daily
for 12 days. Sham-treated euthyroid control rabbits were received only vehicle saline for 12 …
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