Effects of intravenous and oral clonidine on hemodynamic and plasma-catecholamine response due to endotracheal intubation
MP Zalunardo, A Zollinger, DR Spahn, B Seifert… - Journal of clinical …, 1997 - Elsevier
STUDY OBJECTIVE: To investigate the effects of intravenous (IV) versus oral clonidine on
alterations of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and
plasma-catecholamines due to endotracheal intubation. Design: Randomized, double-blind,
placebo-controlled study. Setting: University hospital surgery operating room. PATIENTS: 33
ASA physical status I patients were randomly assigned to either receive clonidine 3 μg/kg IV
immediately prior to anesthesia induction, clonidine 4 μg/kg orally 90 minutes prior to …
alterations of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and
plasma-catecholamines due to endotracheal intubation. Design: Randomized, double-blind,
placebo-controlled study. Setting: University hospital surgery operating room. PATIENTS: 33
ASA physical status I patients were randomly assigned to either receive clonidine 3 μg/kg IV
immediately prior to anesthesia induction, clonidine 4 μg/kg orally 90 minutes prior to …
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