BACKGROUND: Epidemiologic studies have shown that serum uric acid is a risk factor of
coronary artery disease. In addition to fenofibrate, there is some evidence that atorvastatin
may have a hypouricemic action, but the underlying mechanisms remain speculative.
METHODS: This randomized trial was conducted to investigate the effects of atorvastatin
and simvastatin on uric acid homeostasis in patients treated for primary hyperlipidemia. A
total of 180 patients were enrolled; patients were randomly assigned to 40 mg/d of either …

… Effects of statin treatment on uric acid homeostasis in patients with primary hyperlipidemia …
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Effects of statin treatment on uric acid homeostasis in patients with primary hyperlipidemia …