Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory
L Li, SH Yun, J Keblesh, BL Trommer, H Xiong… - Molecular and Cellular …, 2007 - Elsevier
Learning and memory depend upon poorly defined synaptic and intracellular modifications
that occur in activated neurons. Mitogen activated protein kinase-extracellular regulated
kinase (MAPK-ERK) signaling and de novo protein synthesis are essential aspects of
enduring memory formation, but the precise effector molecules of MAPK-ERK signaling in
neurons are not well defined. Early growth response (Egr) transcriptional regulators are
examples of MAPK-ERK regulated genes and Egr1 (zif268) has been widely recognized as …
that occur in activated neurons. Mitogen activated protein kinase-extracellular regulated
kinase (MAPK-ERK) signaling and de novo protein synthesis are essential aspects of
enduring memory formation, but the precise effector molecules of MAPK-ERK signaling in
neurons are not well defined. Early growth response (Egr) transcriptional regulators are
examples of MAPK-ERK regulated genes and Egr1 (zif268) has been widely recognized as …
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