Electrochemically controlled drug-mimicking protein release from iron-alginate thin-films associated with an electrode

Z Jin, G Güven, V Bocharova, J Halámek… - … applied materials & …, 2012 - ACS Publications
Novel biocompatible hybrid-material composed of iron-ion-cross-linked alginate with
embedded protein molecules has been designed for the signal-triggered drug release.
Electrochemically controlled oxidation of Fe2+ ions in the presence of soluble natural
alginate polymer and drug-mimicking protein (bovine serum albumin, BSA) results in the
formation of an alginate-based thin-film cross-linked by Fe3+ ions at the electrode interface
with the entrapped protein. The electrochemically generated composite thin-film was …

[引用][C] Electrochemically Controlled Drug-Mimicking Protein Release from Iron-Alginate Thin-Films Associated with an Electrode

J Zhiyuan, G Güray, B Vera, H Jan, T Ihor, M Sergiy… - 2012
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