Electrospun silk material systems for wound healing

SE Wharram, X Zhang, DL Kaplan… - Macromolecular …, 2010 - Wiley Online Library
The functional properties of six distinct electrospun silk material groups were evaluated to
assess conformational and biocompatible characteristics related to wound dressings. In a
hydrated state, all six silk matrices exhibited absorption, water vapor transmission, oxygen
permeation and enzymatic biodegradation suitable for full‐thickness wound sites.
Employing constrained drying techniques, silk concentration was a determinate factor
influencing material structural properties related to the storage and distribution of such …

Electrospun Silk Material Systems for Wound Healing

SP McCarthy, SE Wharram, X Zhang, DL Kaplan - abstracts.biomaterials.org
Methods: The most useful properties in a full thickness burn wound dressing include the
ability to provide an impermeable barrier to bacterial pathogens, manage wound site edema
and dehydration, and support time synchronized antibiotic, immunological, and tissue
regeneration biotherapies. Capitalizing on the unique fiber morphology of variant
electrospun silk/PEO blends, this research explored the conformational and biofunctional
properties of six distinct PEO extracted silk material systems for potential utility as full …
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