… endothelial sprouting in aortic ring assays. However, the role of endothelial‐FAK in tumour
angiogenesis … additionally identify endothelial FAK as a possible anti‐angiogenic target thus …

… Endothelial-FAK deletion inhibits tumour angiogenesis in … control of cancer progression and
tumour angiogenesis we need to … when FAK is activated in vivo during tumour angiogenesis. …

… FAK is expressed ubiquitously and has essential roles in a number of cellular processes, …
endothelial-specific loss of FAK in Pdgfb-iCreER T2 ;FAK fl/fl mice inhibit tumour angiogenesis …

… -dependent signaling that is required for the elevated … requirements of EC-FAK-Y397
and EC-FAK-Y861 phosphorylation in the regulation of EC signaling and tumor angiogenesis …

… and resulted in reduced tumor angiogenesis and tumor growth (21). … required to elucidate
the clinical relevance of these changing functions of EC-FAK in regulating tumor angiogenesis…

… that tumor angiogenesis is mediated by endothelial FAK is … by reduced tumor growth in mice
with an inducible endothelial FAK … Endothelial FAK has also been implicated as an essential …

… These tumour sub-types require different treatments and have different … in tumour angiogenesis.
However, the association between breast cancer sub-types and tumour endothelial-FAK …

… FAK in tumor-associated endothelial cells (ECs). Conditional kinase-dead … This result is
consistent with the need for c-Src activity in mediating full FAK … VEGFA and tumour angiogenesis …

… Endothelial specific Rac1 knockout mice embryos die in utero (at E9.5) due to impaired
angiogenesis, suggesting an essential role of … , it is only essential for tumour angiogenesis in the …

… in angiogenesis during embryonic development and cancer … kinase-independent functions
for FAK in endothelial cells and … , however, FAK's kinase activity was found to be required for …