Today, attention to entrepreneurship is one of the important concerns of institutions and centers, including universities. University, as a living human system, needs agility to flourish and learn from changes, so that the change is a natural and inevitable part of organizational life, not a separate sector and a threatening event. The purpose of this study was to present a model of agility in an entrepreneurial university with a knowledge management approach. The research is based on the objective, applied, qualitative approach (based on systematic data collection), using the theory-based method of data. The statistical population of the study consisted of professors from academics and experts in human resources management, entrepreneurship and knowledge management. The sample was selected with the aim of reaching theoretical saturation through a snowball targeted sampling. Finally, the sample included 25 subjects. Data gathering from key informants was conducted using exploratory interviewing method and data analysis based on the theory of data, using theoretical coding. The resulting pattern indicates that the main category that leads to the agility outcomes of the entrepreneurial university is the agility requirements of the Entrepreneurial University for enrichment, customer satisfaction, and the provision of solutions to them. Through agility and agility enablers, power was seen by the agility of the organization at the entrepreneurial university with a knowledge management approach. Introduction The term agility in the dictionary means fast, agile, fast and easy moving, and the ability to think fast with a clever method used to react to changes in the environment and exploit those changes as opportunities. Has been introduced (Hornby et al, 2000). Mates & Yakalan (2005) defined agility as follows: the ability of an organization to discover (identify) changes (which can be opportunities or threats or a combination of them) in their business environment and give an answer quickly focusing on customers and stakeholders through reorganization, resources, processes and strategies. An organization that is designed in an agile manner has a unique organizational structure. Therefore, for their success and survival, organizations need to create a position, system and structure that will benefit both from its human resources capacity and commitment to continuous learning at all levels of the organization, and will lead to continuous acquisition and effective use of new knowledge. One of these organizations is the University of Entrepreneurship. Today, attention to entrepreneurship is one of the important concerns of institutions and centers, including universities. The entrepreneurial university theory is one of the models proposed to explain the new role of universities with the important feature of broader engagement with the community. According to this theory, some higher education systems are coordinated with changes in their programs, with economic development and labor market, and by implementing entrepreneurship projects at universities, innovative graduates and Educate Creative. One of these programs is the agility of the entrepreneurial universities (Gibb, 2012).The United Nations Scientific and Cultural Organization (2004) described the new universities as one of the 21st century global higher education: "The place where entrepreneurship skills in higher education are designed to alleviate the capabilities of graduates and to become the founders of work develops.” Zhang et al. (2016) argue that universities are no longer part of separate knowledge, but are institutions engaging increasingly in business with business partnerships. Higher …