… understanding of enzyme structure and dynamics, we are only beginning to be able to
design novel enzymes. One can now begin to trace the functional evolution of enzymes using …

… As enzymes are involved in all steps of metabolic … of enzymes is important for drug design
like design of enzyme inhibitors which has been a mainstay of molecular design. Enzyme …

A limited number of publicly available resources provide access to enzyme kinetic parameters.
These have been compiled through manual data mining of published papers, not from …

… and informatics studies to P. falciparum DHFR enzyme. Modelling studies on DHFR … , most
of the information regarding the structure and enzyme-inhibitor interactions of this enzyme are …

… Strategy for functional profiling of an enzyme superfamily To date, informatics or computational
strategies for predicting GT1 enzyme activity have made only limited progress, as further …

… The following chapters discuss biomolecular interactions, enzyme action, gene transmission,
signal transduction, and biomacromolecular informatics. The author concludes with …

… Target Informatics Platform (TIP), a novel structural informatics … Our analysis underscores
the utility of a structural informatics … -converting enzyme inhibitors on bradykinin metabolism in …

… Informatics by building a strategic framework of computational biophysical tools and informatics
… Non-enzymatic spontaneous chemical degradation of biologic drug products during …

… cAMP hydrolyzing phosphodiesterase 4 (PDE4) enzyme family, which has been implicated
in … The fact that all PDE4 enzymes have been highly conserved over evolution suggests that …

… At Eidogen-Sertanty, we have developed a structural informatics database that utilizes …
human enzyme close off a portion of the binding pocket that is accessible in the fungal enzyme, …