Background The skin barrier is vital for protection against environmental threats including
insults caused by skin‐resident microbes. Dysregulation of this barrier is a hallmark of atopic
dermatitis (AD) and ichthyosis, with variable consequences for host immune control of
colonizing commensals and opportunistic pathogens. While Malassezia is the most
abundant commensal fungus of the skin, little is known about the host control of this fungus
in inflammatory skin diseases. Methods In this experimental study, MC903‐treated mice …

The skin barrier is vital for protection against environmental threats including insults caused
by skin-resident microbes. Dysregulation of this barrier is a hallmark of atopic dermatitis (AD)
and ichthyosis, with variable consequences for host immune control of colonizing
commensals and opportunistic pathogens. While Malassezia is the most abundant
commensal fungus of the skin, little is known about the host control of this fungus in
inflammatory skin diseases. Here we show that in barrier-impaired skin, Malassezia …