Epithelial‐to‐mesenchymal transition transcription factors in cancer‐associated fibroblasts
J Baulida - Molecular oncology, 2017 - Wiley Online Library
Beyond inducing epithelial‐to‐mesenchymal transcription (EMT), transcriptional factors of
the Snail, ZEB and Twist families (EMT‐TF s) control global plasticity programmes affecting
cell stemness and fate. Literature addressing the reactivation of these factors in adult tumour
cells is very extensive, as they enable cancer cell plasticity and fuel both tumour initiation
and metastatic spread. Incipient data reveal that EMT‐TF s are also expressed in fibroblasts,
providing these with additional properties. Here, I will review recent reports on the …
the Snail, ZEB and Twist families (EMT‐TF s) control global plasticity programmes affecting
cell stemness and fate. Literature addressing the reactivation of these factors in adult tumour
cells is very extensive, as they enable cancer cell plasticity and fuel both tumour initiation
and metastatic spread. Incipient data reveal that EMT‐TF s are also expressed in fibroblasts,
providing these with additional properties. Here, I will review recent reports on the …
Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts
J Baulida i Estadella - Molecular Oncology. 2017 Jul; 11 (7): 847 …, 2017 - repositori.upf.edu
Beyond inducing epithelial-to-mesenchymal transcription (EMT), transcriptional factors of the
Snail, ZEB and Twist families (EMT-TFs) control global plasticity programmes affecting cell
stemness and fate. Literature addressing the reactivation of these factors in adult tumour
cells is very extensive, as they enable cancer cell plasticity and fuel both tumour initiation
and metastatic spread. Incipient data reveal that EMT-TFs are also expressed in fibroblasts,
providing these with additional properties. Here, I will review recent reports on the …
Snail, ZEB and Twist families (EMT-TFs) control global plasticity programmes affecting cell
stemness and fate. Literature addressing the reactivation of these factors in adult tumour
cells is very extensive, as they enable cancer cell plasticity and fuel both tumour initiation
and metastatic spread. Incipient data reveal that EMT-TFs are also expressed in fibroblasts,
providing these with additional properties. Here, I will review recent reports on the …
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