[PDF][PDF] Evaluation of antiulcer activity of Ocimum sanctum in rats

GR Ghangale, M Tushar, ND Jadhav - Veterinary world, 2009 - veterinaryworld.org
GR Ghangale, M Tushar, ND Jadhav
Veterinary world, 2009veterinaryworld.org
Aqueous extract of Ocimum sanctum was evaluated for its Antiulcer activity against methanol
induced ulcer in Wistar rats. The aqueous extract of Ocimum sanctum at the dose rate of
100mg/kg an 200 mg/kg per orally exhibited significant protection against ethanol induced
gastric ulceration. The present investigation revealed that Ocimum sanctum exhibited
significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby
reducing mucosal damage.
Abstract
Aqueous extract of Ocimum sanctum was evaluated for its Antiulcer activity against methanol induced ulcer in Wistar rats. The aqueous extract of Ocimum sanctum at the dose rate of 100mg/kg an 200 mg/kg per orally exhibited significant protection against ethanol induced gastric ulceration. The present investigation revealed that Ocimum sanctum exhibited significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby reducing mucosal damage.
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