In this paper, we evaluate and compare the performance of single-copy and multiple-copy routing protocols in a realistic Vehicular Delay Tolerant Network (VDTN) scenario. The simulations are conducted with the Opportunistic Network Environment (ONE) simulator. The performance is analyzed using delivery probability, overhead ratio, average latency, average number of hops and average buffer time metrics. The simulation results show that multiple-copy protocols perform better in terms of delivery probability compared with singlecopy protocol. The single-copy protocol uses the highest average number of hops and higher average latency compared with multiple-copy protocols. Maxprop achieves the highest delivery ratio and lowest average latency. Spray and wait results are the lowest for overhead ratio, but the longest for average buffer time. First contact have a short buffer time, but it uses a big number of hops.