Evolution of a flipped pathway creates metabolic innovation in tomato trichomes through BAHD enzyme promiscuity

P Fan, AM Miller, X Liu, AD Jones, RL Last - Nature Communications, 2017 - nature.com
Plants produce hundreds of thousands of structurally diverse specialized metabolites via
multistep biosynthetic networks, including compounds of ecological and therapeutic
importance. These pathways are restricted to specific plant groups, and are excellent
systems for understanding metabolic evolution. Tomato and other plants in the nightshade
family synthesize protective acylated sugars in the tip cells of glandular trichomes on stems
and leaves. We describe a metabolic innovation in wild tomato species that contributes to …

Evolution of a flipped pathway creates metabolic innovation in tomato trichomes through BAHD enzyme promiscuity.

FPX Fan PengXiang, AM Miller, LXX Liu XiaoXiao… - 2017 - cabidigitallibrary.org
Plants produce hundreds of thousands of structurally diverse specialized metabolites via
multistep biosynthetic networks, including compounds of ecological and therapeutic
importance. These pathways are restricted to specific plant groups, and are excellent
systems for understanding metabolic evolution. Tomato and other plants in the nightshade
family synthesize protective acylated sugars in the tip cells of glandular trichomes on stems
and leaves. We describe a metabolic innovation in wild tomato species that contributes to …
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