[图书][B] Examination of the cytoprotective role of Sirtuin-1 in the renal medulla
W He - 2010 - search.proquest.com
W He
2010•search.proquest.comResults........................................................................................................... 45
Discussion...................................................................................................... 62 v IV. THE ANTI-
OXIDANT ACTIVITY OF SIRT1 IS PARTIALLY MEDIATED THROUGH INCREASING COX2
EXPRESSION................................................ 67 Introduction................................................................
.................................... 67 Results...........................................................................................................
69 Discussion..................................................................................................... 77 V. RENAL …
Discussion...................................................................................................... 62 v IV. THE ANTI-
OXIDANT ACTIVITY OF SIRT1 IS PARTIALLY MEDIATED THROUGH INCREASING COX2
EXPRESSION................................................ 67 Introduction................................................................
.................................... 67 Results...........................................................................................................
69 Discussion..................................................................................................... 77 V. RENAL …
Results........................................................................................................... 45
Discussion...................................................................................................... 62
v
IV. THE ANTI-OXIDANT ACTIVITY OF SIRT1 IS PARTIALLY MEDIATED THROUGH INCREASING COX2 EXPRESSION................................................ 67
Introduction.................................................................................................... 67
Results........................................................................................................... 69
Discussion..................................................................................................... 77
V. RENAL MEDULLARY INTERSTITIAL COX2 IN THE REGULATION OF RENAL SODIUM EXCRETION AND BLOOD PRESSURE................................ 82
Introduction.................................................................................................... 82
Results........................................................................................................... 84
Discussion...................................................................................................... 95
VI. A RENAL MEDULLARY INTERSTITIAL CELL SPECIFIC INDUCIBLE CRE MOUSE, TENASCIN-C-CreER2-EGFP KNOCKIN MOUSE............................... 99
Introduction.................................................................................................... 99
Results.......................................................................................................... 101
Discussion..................................................................................................... 112
VII. CONCLUSIONS AND FUTURE DIRECTION............................................. 114
Conclusions................................................................................................ 114
Future Directions........................................................................................ 117
vi
REFERENCES.................................................................................................. 128
vii
LIST OF TABLES
Table Page 1. Microarray reveals several genes that are selectively expressed in cultured
renal medullary interstitial cells (RMICs)............................................................ 102
viii
LIST OF FIGURES
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