Exercise-modulated epigenetic markers and inflammatory response in COPD individuals: A pilot study
IRV da Silva, CLP de Araujo, GP Dorneles… - Respiratory physiology …, 2017 - Elsevier
The study investigated the effects of exercise on epigenetic signals and systemic cytokine
levels in chronic obstructive pulmonary disease (COPD) individuals. Ten participants of a
pulmonary rehabilitation program were submitted to 24 sessions of a supervisioned exercise
protocol thrice-weekly (90 min/session). Blood samples were collected at baseline, after the
1st session, before and after the 24th session. A DNA hypomethylation status was observed
after the 1st session when compared at baseline, while global histone H4 acetylation status …
levels in chronic obstructive pulmonary disease (COPD) individuals. Ten participants of a
pulmonary rehabilitation program were submitted to 24 sessions of a supervisioned exercise
protocol thrice-weekly (90 min/session). Blood samples were collected at baseline, after the
1st session, before and after the 24th session. A DNA hypomethylation status was observed
after the 1st session when compared at baseline, while global histone H4 acetylation status …
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