… the safety and efficacy of favipiravir in patients with EVD, the … emergency trial in the context
of a large Ebola outbreak and to … effectiveness of favipiravir in reducing mortality and viral load …

… trial, in which all patients would receive favipiravir along with standardized care. The objectives
of the trial … of an emergency trial in the context of a large Ebola outbreak, and to collect …

… No apparent survival benefit as compared to historical … of conducting trials in Ebola treatment
units during an outbreak … studies on the treatment of influenza with favipiravir, which was …

… including the broad-spectrum antiviral drug favipiravir, monoclonal antibody cocktails, small
… 2016 EVD outbreak [16–19]. After completion of the JIKI clinical trial for favipiravir in Guinea […

… heels of the JIKI trial, which was a historically controlled, single-arm, proof-of-concept trial
in Guinea. The outcome from this study of 111 patients was that favipiravir monotherapy may …

… experiments and expected in the JIKI trial. Accordingly, a first … In addition to historical
preclinical data available from the … Ebola virus and treated with ascending doses of favipiravir. Left…

… favipiravir tolerance and efficacy in patients with Ebola virus (… tolerance and efficacy in
patients with Ebola virus disease (… a historically-controlled, single-arm proof-of-concept trial to …

… Full, or interim results of clinical trials for a number of experimental therapeutics have recently
… Experimental treatment with favipiravir for Ebola virus disease (the JIKI Trial): a historically …

… The historically controlled, single-arm proof-of-concept JIKI … successive experiments with
increasing doses of favipiravir … patients treated with oral 1,200 mg BID favipiravir (JIKI trial), …

… treating influenza virus infections. In the setting of the pioneer Phase II JIKI trial, 126 patients
with acute Ebola virus disease … JIKI trial, favipiravir treatment was offered in the Coyah Ebola …