FANCM limits meiotic crossovers
W Crismani, C Girard, N Froger, M Pradillo, JL Santos… - Science, 2012 - science.org
… The biochemical properties of FANCM helicases are likely similar at mitosis and meiosis.
We suggest that FANCM processes meiotic DSB repair intermediates, possibly D loops, driving …
We suggest that FANCM processes meiotic DSB repair intermediates, possibly D loops, driving …
FANCM limits meiotic crossovers in Brassica crops
A Blary, A Gonzalo, F Eber, A Bérard… - Frontiers in Plant …, 2018 - frontiersin.org
… frequency (~32%, Welch's t-test; p-value < 0.013) in the progeny of fancm mutants … in
crossover frequency observed for three intervals suggests that FANCM limits crossover formation in …
crossover frequency observed for three intervals suggests that FANCM limits crossover formation in …
FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers
C Girard, W Crismani, N Froger, J Mazel… - Nucleic acids …, 2014 - academic.oup.com
… of FANCM in the control of meiotic CO formation raises the question whether other FA proteins
limit meiotic COs, or if the FANCM meiotic … We propose that FANCM and its direct DNA-…
limit meiotic COs, or if the FANCM meiotic … We propose that FANCM and its direct DNA-…
Multiple mechanisms limit meiotic crossovers: TOP3α and two BLM homologs antagonize crossovers in parallel to FANCM
M Séguéla-Arnaud, W Crismani… - Proceedings of the …, 2015 - National Acad Sciences
… almost the theoretical maximum of ∼125 CO per meiosis, … -R640X fancm and the recq4a
recq4b fancm triple mutants … examined meiotic chromosome behavior in recq4a recq4b fancm, …
recq4b fancm triple mutants … examined meiotic chromosome behavior in recq4a recq4b fancm, …
Unleashing meiotic crossovers in hybrid plants
JB Fernandes, M Séguéla-Arnaud… - Proceedings of the …, 2018 - National Acad Sciences
… genes that redundantly limit meiotic crossovers in Arabidopsis… , the fancm mutation, which
increases meiotic recombination … meiosis in the Col recq4 figl1 and recq4 figl1 fancm, which …
increases meiotic recombination … meiosis in the Col recq4 figl1 and recq4 figl1 fancm, which …
Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals
… Meiotic crossover numbers are tightly regulated within a narrow range, despite an excess …
FANCM as a meiotic anti-crossover factor in mammals. We use unique large-scale crossover …
FANCM as a meiotic anti-crossover factor in mammals. We use unique large-scale crossover …
Unleashing meiotic crossovers in crops
… FANCM was shown to limit crossovers in a Brassica rapa … We tested the effect of recq4,
fancm and figl1 mutations on … and copy number of RECQ4, FANCM and FIGL1 in flowering …
fancm and figl1 mutations on … and copy number of RECQ4, FANCM and FIGL1 in flowering …
What limits meiotic crossovers?
W Crismani, R Mercier - Cell Cycle, 2012 - Taylor & Francis
… meiotic function of FANCM was previously described, meiotic recombination in Arabidopsis
fancm … lished a function of Arabidopsis FANCM in regulating meiotic crossover formation but …
fancm … lished a function of Arabidopsis FANCM in regulating meiotic crossover formation but …
[HTML][HTML] Control of meiotic crossing over in plant breeding
SR Strelnikova, RA Komakhin - Vavilov Journal of Genetics and …, 2023 - ncbi.nlm.nih.gov
… meiotic recombination frequency increase upon inactivation of the FANCM, TOP3α, RECQ4,
FIGL1 crossover … the frequency of meiotic recombination has significant limitations. Probably…
FIGL1 crossover … the frequency of meiotic recombination has significant limitations. Probably…
FANCM promotes class I interfering crossovers and suppresses class II non-interfering crossovers in wheat meiosis
SD Desjardins, J Simmonds, I Guterman… - Nature …, 2022 - nature.com
… Here, we observe that FANCM maintains the obligate crossover in … at least one crossover,
by localizing class I crossover protein HEI10 at pachytene. … FANCM limits class II crossovers …
by localizing class I crossover protein HEI10 at pachytene. … FANCM limits class II crossovers …
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- meiotic crossover distribution
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