Fabrication and in vitro characterization of Niosomal formulations for controlled delivery of ranitidine HCl
The present study was aimed to fabricate and evaluate ranitidine HCl loaded niosomal for-
mulation for in vitro pharmacokinetic behaviour. Formulating it as niosomal formulation might
be quite advantageous for prolonging the duration of pharmacological action and improved
bioavailability. In the present study niosomal formulation were prepared by using most
documented thin film hydration technique by using various grades of surfactants (span 20,
40, 60, and 80) in varying ratios with cholesterol, negative charge inducer; phosphatidic acid …
mulation for in vitro pharmacokinetic behaviour. Formulating it as niosomal formulation might
be quite advantageous for prolonging the duration of pharmacological action and improved
bioavailability. In the present study niosomal formulation were prepared by using most
documented thin film hydration technique by using various grades of surfactants (span 20,
40, 60, and 80) in varying ratios with cholesterol, negative charge inducer; phosphatidic acid …
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