Fabrication of inverted colloidal crystal poly (ethylene glycol) scaffold: a three-dimensional cell culture platform for liver tissue engineering
H Shirahama, SK Kumar, WY Jeon, MH Kim… - JoVE (Journal of …, 2016 - jove.com
The ability to maintain hepatocyte function in vitro, for the purpose of testing xenobiotics'
cytotoxicity, studying virus infection and developing drugs targeted at the liver, requires a
platform in which cells receive proper biochemical and mechanical cues. Recent liver tissue
engineering systems have employed three-dimensional (3D) scaffolds composed of
synthetic or natural hydrogels, given their high water retention and their ability to provide the
mechanical stimuli needed by the cells. There has been growing interest in the inverted …
cytotoxicity, studying virus infection and developing drugs targeted at the liver, requires a
platform in which cells receive proper biochemical and mechanical cues. Recent liver tissue
engineering systems have employed three-dimensional (3D) scaffolds composed of
synthetic or natural hydrogels, given their high water retention and their ability to provide the
mechanical stimuli needed by the cells. There has been growing interest in the inverted …
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