Background: Currently, there is no pharmaceutical intervention to treat or delay pathological
cognitive decline or Alzheimer's disease and related dementias (ADRD). Multidomain
lifestyle interventions are increasingly being studied as a non-pharmacological solution to
enhance cognitive reserve, maintain cognition, and reduce the risk of or delay ADRD.
Review of completed and prospective face-to-face (FTF) and digital multidomain
interventions provides an opportunity to compare studies and informs future interventions …