Fatality involving ocfentanil documented by identification of metabolites
N Allibe, C Richeval, M Phanithavong… - Drug testing and …, 2018 - Wiley Online Library
… could improve the detection window in biological matrices, data about the metabolism of OcF
are … , we report a fatality case involving OcF documented by identification of its metabolites. …
are … , we report a fatality case involving OcF documented by identification of its metabolites. …
Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes
M Mardal, SS Johansen, AB Davidsen… - Forensic Science …, 2018 - Elsevier
… O-demethylated metabolite of ocfentanil was identified as the main metabolite in blood and
… Interestingly, metabolites were also recorded with high signal intensities in brain tissue. The …
… Interestingly, metabolites were also recorded with high signal intensities in brain tissue. The …
Acute intoxications and fatalities from illicit fentanyl and analogues: an update
S Pichini, R Solimini, P Berretta, R Pacifici… - Therapeutic drug …, 2018 - journals.lww.com
… symptoms, eventual death cause, and metabolites detected in … websites, to identify
documentation published by international … Ocfentanil was detected in different biological …
documentation published by international … Ocfentanil was detected in different biological …
A 2017–2019 update on acute intoxications and fatalities from illicit fentanyl and analogs
P Brunetti, F Pirani, J Carlier, R Giorgetti… - Journal of Analytical …, 2021 - academic.oup.com
… fatalities might have gone unnoticed, and research efforts should focus on metabolite identification
… Three ocfentanil-related deaths and a series of three intoxications occurred in France …
… Three ocfentanil-related deaths and a series of three intoxications occurred in France …
A case report of carfentanil-related fatality in France
JM Gaulier, C Richeval, M Phanithavong… - … Analytique et Clinique, 2019 - Elsevier
… of metabolite (especially NorCaF) suggests a sudden death of the … and several deaths due
to intoxication were recorded in … LC-HRMS and 12 metabolites were identified. In this in vitro …
to intoxication were recorded in … LC-HRMS and 12 metabolites were identified. In this in vitro …
Case report: relevance of metabolite identification to detect new synthetic opioid intoxications illustrated by U-47700
C Richeval, JM Gaulier, L Romeuf, D Allorge… - International journal of …, 2019 - Springer
… a fatality case related to U-47700 intake, this work aims to investigate and discuss the relevance
of identification of CYP- and UGT-dependent metabolites of … is intended to document the …
of identification of CYP- and UGT-dependent metabolites of … is intended to document the …
Ocfentanil in France: Seven case reports (2016–2018)
N Allibe, F Billault, C Moreau, A Marchard… - … Analytique et Clinique, 2019 - Elsevier
… high risk of overdose and death, as illustrated with acetylfentanyl, … to their high opioid potency,
and their extensive metabolism. … involving OcF presented in this article, three are non-fatal, …
and their extensive metabolism. … involving OcF presented in this article, three are non-fatal, …
Metabolic pathways and potencies of new fentanyl analogs
M Wilde, S Pichini, R Pacifici, A Tagliabracci… - Frontiers in …, 2019 - frontiersin.org
… cases or fatalities, the presence of metabolites can be crucial … What has been documented
for fentanyl metabolism typically … reactions only play a minor role in metabolism of ocfentanil. …
for fentanyl metabolism typically … reactions only play a minor role in metabolism of ocfentanil. …
Postmortem toxicology of new synthetic opioids
M Concheiro, R Chesser, J Pardi… - Frontiers in …, 2018 - frontiersin.org
… acute or a delayed-death evaluating the metabolite-to-parent … main metabolites identified in
urine were the nor-metabolite, … For ocfentanyl, the predominant metabolite detected in blood, …
urine were the nor-metabolite, … For ocfentanyl, the predominant metabolite detected in blood, …
Fatal cases involving new psychoactive substances and trends in analytical techniques
E Ferrari Júnior, BHM Leite, EB Gomes… - Frontiers in …, 2022 - frontiersin.org
… NPS metabolites and respective elimination pathways are usually unknown, making it difficult
the detection and confirmation of the drug involved in the fatal … The metabolite identification …
the detection and confirmation of the drug involved in the fatal … The metabolite identification …