We conducted a feasibility study to test an intervention to reduce medication omissions without documentation using nurse-initiated recall cards and medication chart checking at handover. No significant difference in the omission rate per 100 medications was found, although after adjusting for hospital and patient age, a significant effect occurred in the intervention group (n= 262 patients) compared with the control group (n= 272). This intervention may reduce medication omissions without documentation, requiring further study within larger samples.